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March Madness odds: Opening lines for every First Round game

Now that the NCAA Tournament bracket has dropped, March Madness odds have also emerged. Who is favored in each First Round game?

Selection Sunday is complete and the NCAA Tournament has been revealed.

Gonzaga, Arizona, Baylor and Kansas picked up No. 1 seed status as the remainder of the bracket came together with 68 total teams ready to rock and roll.

It’ll all tip-off with First Four matchups on Tuesday and Wednesday before the Madness really gets going on Thursday and Friday.

What lines did the oddsmakers come up with for this year’s First Four and First Round?

All odds via WynnBet

March Madness odds for every First Round game in 2022

First Four NCAA Tournament Odds

12 Indiana vs. 12 Wyoming: +4, O/U 132.5
16 Texas A&M CC vs. 16 Texas Southern: -2.5, 136
16 Bryant vs.16  Wright State: -1, 153.5
11 Rutgers vs. 11 Notre Dame: -1, 133

West Region NCAA Tournament Odds

16 Georgia St vs. 1 Gonzaga: -23, 148.5
9 Memphis vs. 8 Boise State: +2.5, 133.5
12 NM State vs. 5 UConn: -6, 133.5
13 Vermont vs. 4 Arkansas: -4.5, 140
14 Montana St vs. 3 Texas Tech: -14.5, 131
10 Davidson vs. 7 Michigan St: -1.5, 140
15 CS Fullerton vs. 2 Duke: -17, 143

Midwest Region NCAA Tournament Odds

9 Creighton vs. 8 San Diego St: -2.5, 120.5
12 Richmond vs. 5 Iowa: -9, 151.5
13 South Dakota St vs. 4 Providence: -1.5, 148.5
11 Iowa St vs. 6 LSU: -5, 126
14 Colgate vs. 3 Wisconsin: -7, 139.5
10 Miami vs. 7 USC: -1.5, 141.5
15 Jacksonville St vs. 2 Auburn: -16.5, 139

South Region NCAA Tournament Odds

9 TCU vs. 8 Seton Hall, +1, 129
12 UAB vs. 5 Houston: -8, 136.5
13 Chattanooga vs. 4 Illinois: -7, 136.5
11 Michigan vs. 6 Colorado St: +2.5, 139.5
14 Longwood vs. 3 Tennessee: -16.5, 133
10 Loyola-Chicago vs. 7 Ohio St: +2, 133
15 Delaware vs. 2 Villanova: -15, 133

East Region NCAA Tournament Odds

16 Norfolk St vs. 1 Baylor: -20.5, 137.5
9 Marquette vs. 9 UNC: -4, 151.5
13 Akron vs. 4 UCLA: -13.5, 129
11 Virginia Tech vs. 6 Texas: -1, 125.5
14 Yale vs. 3 Purdue: -14.5, 143
10 San Francisco vs. 7 Murray St: +1.5, 138.5
15 St. Peter’s vs. 2 Kentucky: +16, 133

In just a few days time the college basketball world will get to enjoy all the buzzer-beating, cinderella-story, bracket-busting action.

Don’t waste time putting in your picks and laying down your bets because it’ll be here before you know it.

For more NCAA basketball news, analysis, opinion and features, check out more from the FanSided college basketball section to stay on top of the latest action.


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